I didn't begin to do justice to the issue of cause and effect which is of such overriding importance in the practice of medicine, both in diagnosis and therapy. With respect to the interpretation of the history, of the physical examination, of laboratory data and of images. When a patient reports, for example, impairment of vision, whether this complaint is the result of smudged glasses or corneal edema, cataract, inflammation, hemorrhage, retinal degeneration, vascular disorder,