Dear Marion, Most of the day, I've spent reading Hawthorne's Scarlet Letter, my acquaintance with which is long overdue. I started to read it today because it's an assignment for my grandson Benjamin, now in 11th grade. If he wants to talk about the book, I'd like to be able to discuss it with him. Maybe my thoughts will be of no interest, and he'll listen only, if at all, because he is by nature very polite. I found a passage which I thought was relevant to our discussion about medical diagnosis and treatment: "Thus Roger Chillingworth scrutinised his patient carefully, both as he saw him in his ordinary life, keeping an accustomed pathway in the range of thoughts familiar to him, and as he appeared when thrown amidst other moral scenery, the novelty of which might call out something new to the surface of his character. He deemed it essential, it would seem, to know the man, before attempting to do him good. Wherever there is a heart and an intellect, the diseases of the physical frame are tinged with the peculiarities of these. In Arthur Dimmesdale, thought and imagination were so active, and sensibility so intense, that the bodily infirmity would be likely to have its groundwork there. So Roger Chillingworth--the man of skill, the kind and friendly physician--strove to go deep into his patient's bosom, delving among his principles, prying into his recollections, and probing everything with a cautious touch, like a treasure-seeker in a dark cavern. Few secrets can escape an investigator, who has opportunity and licence to undertake such a quest, and skill to follow it up. A man burdened with a secret should especially avoid the intimacy of his physician. If the latter possess native sagacity, and a nameless something more,--let us call it intuition; if he show no intrusive egotism, nor disagreeable prominent characteristics of his own; if he have the power, which must be born with him, to bring his mind into such affinity with his patient's, that this last shall unawares have spoken what he imagines himself only to have thought; if such revelations be received without tumult, and acknowledged not so often by an uttered sympathy as by silence, an inarticulate breath, and here and there a word to indicate that all is understood; if to these qualifications of a confidant be joined the advantages afforded by his recognised character as a physician;--then, at some inevitable moment, will the soul of the sufferer be dissolved, and flow forth in a dark but transparent stream, bringing all its mysteries into the daylight." The passage obviously speaks for itself. As for the role of a personal physician-patient relationship in medical therapy, superfluous or essential, consider the issue of immunization, the simplest and most direct of therapeutic efforts, often mandated by statute or regulation, and readily administered by technicians or nurses. Yet the decision whether any specific immunization should be obtained is often a critical one in the mind of the anxious patient, as for example Merck's latest miracle "Zostavax" to ward off herpes zoster, a vaccine constituted of live inactivated, and sometime not so inactivated virus which costs $200 for a single .65 ml. injection, recommended for _all_ older patients by some government agency, but not covered by Medicare. Who is to decide? Even more compelling, the occasional allergic reactions, anaphylactic or delayed, which can occur in consequence of many injections. Most patients would be less distressed at the biological and financial costs of immunization if they had incurred them on the advice of a physician who had their unique, individual interests at heart. - Just a passing thought. Thank you again, and very much, for your concerns about Margrit. I wish I could see a possibility for Margrit to resume her adventurous independent existence in Detroit; but I don't. I haven't said anything to her and I won't. I'll let future developments speak for themselves. I don't know what the future holds for any of us. At this juncture Margrit is still too weak and too sick, - her diarrhea comes and goes - to make it practical for her to go back. I've mentioned often enough my concerns about her inability to cope with the problems of independent existence isolated as she is in that economically forlorn and disorganized city. The circumstance that I see no solution doesn't mean that a solution might not turn up. If it did, I would welcome it. As for the Caribbean Cruise sponsored by the Nation, it seems inordinately generous of you to offer to accompany Margrit, especially since you yourself have no great enthusiasm for the project. From the perspective of public health, neither Klemens nor I can advise her to make the trip. The presumptive cause of her recurrent diarrhea, clostridium difficile, is recognized as a communicable pathogen responsible for a disease with 25% mortality in susceptible populations. While quarantine is not mandated, and there are no official restrictions on travel, if an epidemic broke out on board ship, a physician who had acquiesced to such gratutitous exposure, would be hard put to defend himself, Notwithstanding such concerns, you should know that Margaret and I are always pleased to have you stay with us to visit Margrit and ourselves in Belmont - when we're in Belmont, - or in Konnarock, when we're in Konnarock, at any time that the spirit so moves you. If you're not taking antibiotics, the risk of clostridium infection is probably low. I apologize for a letter almost entirely lacking in inspiration. I don't believe Hawthorne is at all good for my mind. I'll try to get back to my own writing soon, and then, I hope I'll have more meaningful things to write to you. Jochen