Dear Cyndy, Dr. Peter Lou apparently is taking Monday off. He's not in the office today and his secretary promised that he would return my call tomorrow between patients, which he will be seeing all day. She doesn't know exactly when I'll hear from him. My brother-in-law Peter McPhedran returned my call Saturday evening. I just looked up his credentials on the Internet. Six years younger than myself, he is now Emeritus Professor of Laboratory Medicine and Internal Medicine at Yale. Peter is wonderfully candid and informal, at least with me. When I broached the diagnosis of Henoch Schoenlein Purpura, he said he had never seen a case in an adult, "and of course, if I haven't seen it, it doesn't exist." He promised "to do some research in my way" and call me back. He hasn't yet. Given Peter's extensive exposure to the pathology of diseases associated with bleeding, that brief exchange suggests to me that when several years ago the doctors labeled you with the diagnosis "Henoch Schoenlein Purpura" they were, in the venerable medical tradition, improvising a diagnosis, which would allay your anxieties and buttress their own dignity, but that such an rhetorical exercise is of no predictive value as to what will happen when 5 ml. of sodium fluorescein are injected into to your antecubital vein. My own inclination, as I wrote before, is to consent to the injection on the grounds that it is tolerated well by patients with the most diverse allergic manifestations, such as urticaria and asthma. Ultimately, you will decide whether to tell the retinal surgeon about the purpura, leaving to him the decision how to proceed and possibly creating those obstacles to efficient management of disease which arise when physicians practice "defensive medicine." As soon as I hear from either Peter Lou or Peter McPhedran, I'll forward their advice to you by e-mail. Jochen