Dear Marion, Thank you for your letter. The command "forward" did not produce any text in your letters "How Genes Self-Replicate." I infer that mitosis in the computer memory is less reliable than in the living cell. I neglected to point out in the quotation from Faust: Geheimnisvoll am lichten Tag Laesst sich Natur des Schleiers nicht berauben Und was sie deinem Geist nicht offenbaren mag, Das zwingst du ihr nicht ab mit Hebeln und mit Schrauben. that knowledge does not seem to exist independent of the spirit (Geist) to which it is revealed. For Goethe, if I interpret him correctly, knowledge is not the acquisition or repetition of logical propositions, but an intuitive apperception, a gift of nature which cannot be extorted from her. Goethe wrote: "Ich habe nie ueber das Denken gedacht." I am critical of his reluctance to think about thought. To think about thinking is to exercise the mind in a special way that is very effective. It is primarily by thinking about thought that one discovers ones mistakes. Indeed thinking about thought seems to be to be the unavoidable issue of all cogitation, its natural necessary conclusion. Our intellect tends to be self-correcting. Thought creates intellectual experience, which constitutes a feed-back that in turn modifies and revises the thought which provoked it. I share your admiration of molecular biochemistry. Whether one denominates it as fact or as theory is ultimately of little import. I find in molecular biochemistry's description of the genome an esthetic satisfaction akin to the satisfaction I derive from a great musical composition. I discover reality in the immediate apperception of the experiment, or in the compelling application of the theory, rather than in some remote fantasy- or mythlike construction which makes a mockery of my intuition. I've spent almost the whole day on "estate planning," a task which I find unusually difficult, because by definition, I cannot be the executor of my own estate. The laws are obscure and ambiguous, and very threatening, fraught as they are with heavy penalties. They constitute a challenge with which none of my legatees will be able to contend. As a result, I feel helpless. I keep hoping that tomorrow the sun will shine, but the forecast is for rain. Jochen