Dear Marion, Thank you for your letter. Congenital pessimist that I am, its contents didn't surprise me, because my experience suggested to me that a seventy year old woman with faintness and giddiness, with an elevated white count, afebrile, with minimal cough and a pulmonary infiltrate is ill with something other than pneumonia. That was the logic behind my recent insistent queries about your well-being. I'm much appreciative for your forwarding Dr. Skarda's letter to me, but I don't take it as an invitation or a license to insinuate my thoughts and feelings into your most personal affairs. Obviously you require time to orient yourself to the perplexities and problems that suddenly, unexpectedly present themselves to you. When you are ready, tell me in what way, if any, you would like me involved. By now you should know me well enough, mindful especially of my concerns for Margrit, that I am prepared to involve myself, - better said, to take your problems to heart - to any degree congenial to you. I haven't forwarded your correspondence from Dr. Skarda to Klemens, - and I won't until you give me permission. Would you like me to? Klemens, as you know is sensitive, knowledgeable and intelligent about medical matters, and working at the center of a large medical institution has many colleagues whose opinions and advice are available to him. I would readily discuss your problems with Klemens, if you wished, but there's also no reason, if you wished, why you shouldn't write to Klemens directly. kmeyer@tuftsmedicalcenter.org There is also my brother-in-law, Margaret's youngest brother, Peter McPhedran, peter.mcphedran@yale.edu, now 74 years old, a very experienced hematologist/oncologist who has directed the Yale University Medical School hematology laboratory for many years. I would be pleased, if you wished, to "present your case" to Peter for his opinion and advice. You should also feel free to introduce yourself directly to Peter, e-mail him the clinical data and send him a blood smear. Peter and I have for many years been on very good terms. I like him very much and I have no reservations about quizzing him to my mind's content. I should add, however, that he and I think differently, and sometimes come to diametrically opposite conclusions about medical matters. I am always grateful for his advice and try to learn from him. I don't argue with him but in the end, I keep my own counsel. As I understand it, the threshold issue for you is the extent, if any to which you wish to manage your medical problems yourself. You have the intellectual and emotional resources, not to speak of the scientific training, to function as your own physician. You can't perform surgical operations on yourself, but you can certainly make for yourself _all_ the decisions which are conventially delegated to a hematologist. It would surprise me if already at this incipient stage of the disease there weren't numerous diagnostic, therapeutic, prophylactic options, the simplest being: how often should the blood count be repeated? You can procrastinate and postpone doing anything until such time, if ever, that the disease incapacitates you. You can take the conventional approach and delegate all responsibility to Dr. Skarda and the consultants to whom she will send you. The only thing you can't do is to stop writing to me. I hope to hear from you soon. Jochen