Dear Marion, Yesterday the mailman brought your medical records in a thick envelope which I haven't yet opened. Meanwhile I have done more reading about your pulmonary problem, and more thinking, and venture the following hypothesis: One of the primary determinants of the relatively low oxygen saturation is your physical habitus. At night, when you are recumbent, the diaphragm protrudes into the thorax and pushes against the lungs, limiting vital capacity. ("Orthopnea", shortness of breath when recumbent, is a common, classical manifestation of pulmonary insufficiency (as in cardiac failure.)) Your situation is somehat unusual in that you are not aware of the low oxygen saturation. I believe this to be the case because under some circumstances one adapts to hypoxia, as for example, when one becomes accustomed to breathing at high altitudes. My hypothesis can be tested by ascertaining whether there is consistently difference in the oxygen concentration between the upright position and reumbency. I enjoyed very much "visiting with" you at the airport last Monday, and I look forward to fetching you from there on August 11. Meanwhile I apologize for the brevity of this letter. Various chores are competing for my attention before patients arrive in the early afternoon. Perhaps by now you've recovered from your flight. I hope your visit is evolving according to your expectations. Jochen